首页》回顾》金属结构件的高性能快速响应激光修复技术

超快激光加工在生物医疗领域中应用

演讲课题:超快激光加工在生物医疗领域中应用

演讲人:吴东

演讲摘要:

In recent years, there have been many studies on the growth characteristics of mammalian cells on 2D substrates. However, the growth environment of cells in vivo is mainly in 3D microenvironments, in which the cell growth behaviors are different from that in 2D substrates. Therefore, we could construct polymer-microtube-arrays as tubular 3D microenvironment for studying cell behaviors. An effective microoperating system based on microtube arrays was used for capture, transfer, and release of yeast, embryonic fibroblast mouse cells, and human breast cancer cells. The microtube arrays were used as transparent 3D yeast culture scaffolds to study the effect of 2D tubular confinement on the growth characteristics of budding yeast. The growth tendency and morphological characteristics of yeasts in the microtube was found to have a significant correlation with the diameter of the tubes. Especially in conical microtubes, the captured yeasts showed distinct asymmetrical growth tendency. We believe that this processing method combined with new biological materials has great potential in the area of cell biology and biological tissue engineering.

吴东

中国科学技术大学 教授

Dong Wu is a professor of engineering science at University of Science and Technology of China. He obtained the fifth Chinese Thousand Youth Talents Plan. His current research interests are femtosecond laser 3D microfabrication for microoptical devices, microfluidic chips, micromachines, and biomimetic microstructures. Prof. Wu has published 65 papers in the international journals of Light: Sci & Appl.(Nature publishing group), PNAS, Laser Photon. Rev., Adv. Mater., Adv. Funct. Mater., Small, Lab Chip, Appl. Phys. Lett., Opt. Lett. and so on.

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